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Dr. Daryl A. Bosco, PhD

Dr. Daryl Bosco, PhD

Dr. Daryl A. Bosco is a Professor and Associate Vice Chair of Research in the Department of Neurology at UMass Chan Medical School, Worcester, Massachusetts. In 2024, Dr. Bosco was honored with an Endowed Chair and named the inaugural Paul J. DiMare Chair in Neurodegenerative Disease.

Dr. Bosco’s scientific career began with a Ph.D. in bio-organic chemistry from Brandeis University in Massachusetts and a post-doctoral fellowship at the Scripps Research Institute in California, where she studied protein structure and misfolding in the context of neurodegeneration. Dr. Bosco was then an Instructor at Harvard Medical School in Massachusetts, where she worked in the lab of Professor Robert H. Brown, Jr., MD, DPhil on sporadic amyotrophic lateral sclerosis (ALS).


In 2008, Dr. Bosco established her independent research laboratory at UMass Chan Medical School. The Bosco laboratory is ​​investigating the mechanisms underlying ALS and related disorders such as frontotemporal dementia. In particular, members of the Bosco laboratory are investigating how stress, traumatic brain injury and neuroinflammation contribute to these neurological disorders.