News & Articles
2024
Angel Fund visits UMass Chan for research updates and lab tour
2024 Sharon Timlin Race
2024 Neurology new research space tour in the NERB
guests visit and receive a tour of the new lab space
2024 Angel Fund Gala at UMass Chan Medical School
2024 UMass Chan Convocation Ceremony
Dr. Bosco received a chancellor medal and was named the Paul J. DiMare Chair in Neurodegenerative Disease on September 12, 2024, during the 2024 Convocation ceremony and address by Chancellor Michael F. Collins.
To learn more about the 2024 UMass convocation ceremony, click here.
Paul J. DiMare Chair in Neurodegenerative Disease
Daryl Bosco, PhD, professor of neurology, biochemistry, and molecular biotechnology with the Morningside Graduate School of Biomedical Sciences and associate vice chair of research for the Department of Neurology, joined the UMass Chan family in 2008 and is an innovative researcher in neurodegenerative disease research focusing on amyotrophic lateral sclerosis, frontotemporal dementia, and traumatic brain injury.
Dr. Bosco shares, “It is a tremendous honor to be named the Paul J. DiMare Chair in Neurodegenerative Disease. I am incredibly grateful to the DiMare family and the leadership at UMass Chan for this Endowed Chair. With the Paul J. DiMare endowment, my lab will carry forward Mr. DiMare and his family’s vision of “curing the incurable” by starting new investigations into the causes of sporadic ALS.”
2023
Congratulations to Dr. Bosco, PhD
I am proud to share Daryl Bosco, PhD has ac
cepted her new position, as Associate Vice Chair for research leadership, in basic science.
Dr. Bosco is a pioneer in the area of neurodegenerative disease, with a focus on amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) through laboratory studies in the Bosco Lab. Currently, she receives federal funding from the national Institute for Neurological Disorders and Stroke within NIH, the National Institute of General Medical Sciences within NIH, the Department of Defense, and she is a recent recipient of the Radala Foundation award for ALS research.
As a Professor, Daryl Bosco began her joint tenure with UMass Chan Medical school in 2008 and has a a joint appointment in the Department of Biochemistry and Molecular Biotechnology.
She is also Division Chair of Academic Standards. Daryl Bosco provides advising support to medical and post-doctoral students, graduate students completing their TRAC/QE (Thesis Research Advisory Committee/Qualifying Exam) program, in addition to the development and teaching of curriculum for the Qualifying Exam Course.
2023 Sharon Timlin Race
20th Anniversary
2023 - Angel Fund Annual Gala
2022
Angel Fund 2022
UMass Chan Angel Fund Team 2022
Dr. Bosco and Dr. Brown, Squirrel Run
2019
August
- Eric successfully defends his PhD thesis!
May
- Yen-Chen and Salome were awarded the Morningside Graduate School of Biomedical Sciences Career Development Award.
- Maeve's paper is accepted to Journal of Biological Chemistry (article).
- Salome presents a poster at the Boston Interactive Glia Group Meeting.
- Daryl is awarded an NIH R01 grant "Disruption of nucleocytoplasmic transport in FUS-related neurodegenerative diseases” (Role: MPI with Dr. Clotilde Lagier-Tourenne at MGH).
April
- Daryl is awarded a grant from the Riccio Fund for Neuroscience: "Investigating microglial dysfunction induced by ALS-PFN1". (Role: MPI with Dori Schafer at UMass Chan)
February
- Desiree's translational repression paper is accepted to Human Molecular Genetics (article).
2018
December
- Daryl publishes an invited commentary in PNAS (article).
August
- Daryl is awarded a Healey Award for "Investigating traumatic brain injury (TBI)-induced neurodegeneration". (Role: MPI)
- Maeve successfully defends her PhD thesis!
- FDA approves first drug to use RNA interference for the treatment of peripheral nerve disease , based on discoveries made at UMass Chan Medical School.
July
- Sundar passes his qualifying exam!
May
- Salome passes her qualifying exam!
April
- Daryl is awarded a grant from the Riccio Fund for Neuroscience : " Investigating microglial dysfunction induced by ALS-PFN1". (Role: MPI)
2017
October
- Yen-Chen gives a talk at the UMass Chan Annual Basic Biomedical Sciences Retreat!
September
- Siva successfully defends his PhD thesis!
August
- Daryl receives the Angel Award from the Angel Fund for her dedication to ALS research!
- Frank's poster takes 3rd place at the Combined Summer Undergraduate Research Program Poster Session at UMass Chan!
July
- Salome joins the lab!
May
- UMass Chan News runs an article featuring Jeanne!
March
- A profile of Jeanne is featured by the ALS Association (ALSA)!
- Sundar joins the lab!
- Daryl is awarded Pilot Project Program funding from UMass Chan: Novel ‘Nanobodies’ as a Diagnosis and Therapeutic for ALS! (Role: PI).
January
- Reddy and Jeanne's paper is accepted to Scientific Reports (article).
2016
December - Daryl Gets Tenure!!
June
- Jeanne is awarded a grant from the ALS Association: Disruption of actin dynamics as a pathogenic mechanism in ALS (Role: PI).
May
- Yen-Chen passes her qualifying exam!
January
- Heather joins the lab!
2015
December
- Katie joins the lab!
- Jeanne's contributing research is published in Neuron (article).
September
- Daryl is awarded an R21 from NIH/NINDS: Investigating the response of FUS/TLS to excitotoxic insult! (Role: PI).
- Victoria joins the lab!
August
- Laura obtains her Master's Degree!
- Maeve was awarded the Riccio-Morningside Graduate School of Biomedical Sciences Travel Award!
June
- Melissa successfully defends her PhD thesis!
May
- Yen-Chen joins the lab!
- Eric passes his qualifying exam!
- Siva's paper is accepted to PNAS (article).
March
- Jeanne joins the lab!
2014
December
- Maeve is awarded the Zelda Haidek Memorial Scholarship!
October
- Catherine's paper is accepted to Cell Death and Disease (article).
- Eric joins the lab!
September
- Daryl is awarded an R01 from NIH/NINDS: Misfolded ALS-linked Profilin-1: a novel therapeutic target! (Role: PI).
August
- Melissa's paper is accepted to Journal of Biological Chemistry (article).
- Daryl accepts the ALS Ice Bucket Challenge from Dr. David Weaver (video).
July
- Catherine successfully defends her PhD thesis!
June
- Melissa gives a talk at the annual BMP department retreat!
May
- Catherine and Reddy's FUS review is accepted for ASN Neuro (article).
April
- Maeve passes her qualifying exam!
March
- Reddy successfully defends his PhD thesis!
- Daryl is promoted to Associate Professor!
February
- Cat and Reddy win Young Investigator Scholarships at 9th Annual Drug Discovery for Neurodegeneration Conference in Miami!
2013
August
- Desiree's FUS-Stress granules paper accepted for Molecular Neurodegeneration. (Highly accessed article).
November
- Melissa's SOD1 review is accepted for Frontiers in Cellular Neuroscience (article).
June
- Maeve joins the lab!
May
- Daryl wins the UMass Chan Faculty Award for outstanding research mentoring (Watch the presentation)!
April
- Reddy's FUS-Hyperosmolar Stress paper is accepted for Journal of Cellular Physiology and makes it to the cover (article).
2012
August
- Mutations in Profilin 1 are linked to ALS (article).
July
- Daryl is awarded an R01 from NIH/NINDS: High throughput screening for Compounds to Mitigate Toxicity of FUS/TLS & SOD1 (Role: Co-PI).
May
- Siva and Laura pass their qualifying exams!
April
- Daryl is awarded an R01 from NIH/NINDS: Investigating a Toxic Gain-of-Interaction between FUS/TLS & Stress Granules! (Role: PI).
January
- Kristin joins the lab!
2011
July
- Desiree joins the lab!
June
- Siva joins the lab!
January
- Reddy joins the lab!
2010
October
- SOD1 is linked to sporadic ALS (article).
July
- Daryl is awarded an R01 from NIH/NINDS: Investigation of Post-Translational Modifications in Wild-Type SOD1 in Sporadic ALS! (Role: PI).
May
- Daryl is guest speaker at ICOSA hosted at UMass Chan. Catherine and Melissa present posters.
2009
November
- Melissa joins the lab!
March
- Catherine joins the lab!
February
- Mutations in FUS are linked to ALS (article).
2008
October - Bosco Lab Opens At UMass Chan!!