Skip to main content
Skip to search
Skip to main menu
Skip to footer area
Site Menu
Close
Search the Royer Lab site
Buscar
A-Z
|
Search All UMass Chan Sites
Research
Research
Cancer Target CtBP
Structural Regulation of IRFs
Time-resolved crystallographic analysis
Publications
The Lab
The Lab
The PI
Lab Members
Lab Alumni
Lab Culture
Collaborators
Contact
Additional Resources
About
Admissions
Education
Faculty
Research
Diversity
Giving
Search
Close Search
Royer Lab
Biochemistry and Molecular Biotechnology
Page Menu
Our most recent publications:
Total:
displaying 10 out of
35
results
NADH/NAD+ binding and linked tetrameric assembly of the oncogenic transcription factors CtBP1 and CtBP2
Saturday, January 08, 2022
Author(s):
Heidi Erlandsen,Anne M Jecrois,Jeffry C Nichols,James L Cole,William E Royer
Source:
FEBS letters
NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP)
Monday, February 01, 2021
Author(s):
Jeffry C Nichols,Celia A Schiffer,William E Royer
Source:
The Journal of biological chemistry
Cryo-EM structure of CtBP2 confirms tetrameric architecture
Wednesday, December 02, 2020
Author(s):
Anne M Jecrois,M Michael Dcona,Xiaoyan Deng,Dipankar Bandyopadhyay,Steven R Grossman,Celia A Schiffer,William E Royer
Source:
Structure (London, England : 1993)
Optimizing the refinement of merohedrally twinned P61 HIV-1 protease-inhibitor cocrystal structures
Friday, March 06, 2020
Author(s):
Gordon J Lockbaum,Florian Leidner,William E Royer,Nese Kurt Yilmaz,Celia A Schiffer
Source:
Acta crystallographica. Section D, Structural biology
Active-Site Tryptophan, the Target of Antineoplastic C-Terminal Binding Protein Inhibitors, Mediates Inhibitor Disruption of CtBP Oligomerization and Transcription Coregulatory Activities
Wednesday, May 01, 2019
Author(s):
M Michael Dcona,Priyadarshan K Damle,Francisco Zarate-Perez,Benjamin L Morris,Zaid Nawaz,Michael J Dennis,Xiaoyan Deng,Sudha Korwar,Sahib J Singh,Keith C Ellis,William E Royer,Dipankar Bandyopadhyay,C...
Source:
Molecular pharmacology
Assembly of human C-terminal binding protein (CtBP) into tetramers
Saturday, April 28, 2018
Author(s):
Andrew G Bellesis,Anne M Jecrois,Janelle A Hayes,Celia A Schiffer,William E Royer
Source:
The Journal of biological chemistry
Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity
Saturday, April 29, 2017
Author(s):
Takahide Kouno,Tania V Silvas,Brendan J Hilbert,Shivender M D Shandilya,Markus F Bohn,Brian A Kelch,William E Royer,Mohan Somasundaran,Nese Kurt Yilmaz,Hiroshi Matsuo,Celia A Schiffer
Source:
Nature communications
Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP)
Monday, May 09, 2016
Author(s):
Sudha Korwar,Benjamin L Morris,Hardik I Parikh,Robert A Coover,Tyler W Doughty,Ian M Love,Brendan J Hilbert,William E Royer,Glen E Kellogg,Steven R Grossman,Keith C Ellis
Source:
Bioorganic & medicinal chemistry
Structure-guided design of a high affinity inhibitor to human CtBP
Saturday, January 31, 2015
Author(s):
Brendan J Hilbert,Benjamin L Morris,Keith C Ellis,Janet L Paulsen,Celia A Schiffer,Steven R Grossman,William E Royer
Source:
ACS chemical biology
Insight into the allosteric mechanism of Scapharca dimeric hemoglobin
Friday, October 31, 2014
Author(s):
Jennifer M Laine,Miguel Amat,Brittany R Morgan,William E Royer,Francesca Massi
Source:
Biochemistry
Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design
Tuesday, March 25, 2014
Author(s):
Brendan J Hilbert,Steven R Grossman,Celia A Schiffer,William E Royer
Source:
FEBS letters
Resolution of structural heterogeneity in dynamic crystallography
Thursday, May 23, 2013
Author(s):
Zhong Ren,Peter W Y Chan,Keith Moffat,Emil F Pai,William E Royer,Vukica Šrajer,Xiaojing Yang
Source:
Acta crystallographica. Section D, Biological crystallography
Tertiary and quaternary allostery in tetrameric hemoglobin from Scapharca inaequivalvis
Wednesday, March 06, 2013
Author(s):
Luca Ronda,Stefano Bettati,Eric R Henry,Tara Kashav,Jeffrey M Sanders,William E Royer,Andrea Mozzarelli
Source:
Biochemistry
Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures
Friday, December 16, 2011
Author(s):
Zhong Ren,Vukica Srajer,James E Knapp,William E Royer
Source:
Proceedings of the National Academy of Sciences of the United States of America
Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding
Friday, November 19, 2010
Author(s):
Keith P Romano,Akbar Ali,William E Royer,Celia A Schiffer
Source:
Proceedings of the National Academy of Sciences of the United States of America
Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces
Tuesday, February 16, 2010
Author(s):
Shivender M D Shandilya,Madhavi N L Nalam,Ellen A Nalivaika,Phillip J Gross,Johnathan C Valesano,Keisuke Shindo,Ming Li,Mary Munson,William E Royer,Elena Harjes,Takahide Kono,Hiroshi Matsuo,Reuben S H...
Source:
Structure (London, England : 1993)
Structural insights into interferon regulatory factor activation
Saturday, January 02, 2010
Author(s):
Weijun Chen,William E Royer
Source:
Cellular signalling
Protein conformational dynamics of homodimeric hemoglobin revealed by combined time-resolved spectroscopic probes
Friday, November 20, 2009
Author(s):
Jungkweon Choi,Srinivasan Muniyappan,John T Wallis,William E Royer,Hyotcherl Ihee
Source:
Chemphyschem : a European journal of chemical physics and physical chemistry
Ligand migration and cavities within Scapharca Dimeric HbI: studies by time-resolved crystallo-graphy, Xe binding, and computational analysis
Tuesday, November 17, 2009
Author(s):
James E Knapp,Reinhard Pahl,Jordi Cohen,Jeffry C Nichols,Klaus Schulten,Quentin H Gibson,Vukica Srajer,William E Royer
Source:
Structure (London, England : 1993)
Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5
Tuesday, October 07, 2008
Author(s):
Weijun Chen,Suvana S Lam,Hema Srinath,Zhaozhao Jiang,John J Correia,Celia A Schiffer,Katherine A Fitzgerald,Kai Lin,William E Royer
Source:
Nature structural & molecular biology
Contribution of Ser386 and Ser396 to activation of interferon regulatory factor 3
Tuesday, April 29, 2008
Author(s):
Weijun Chen,Hema Srinath,Suvana S Lam,Celia A Schiffer,William E Royer,Kai Lin
Source:
Journal of molecular biology
Time-resolved x-ray crystallography of heme proteins
Friday, April 25, 2008
Author(s):
Vukica Srajer,William E Royer
Source:
Methods in enzymology
Ligand migration and binding in the dimeric hemoglobin of Scapharca inaequivalvis
Friday, November 16, 2007
Author(s):
Karin Nienhaus,James E Knapp,Pasquale Palladino,William E Royer,G Ulrich Nienhaus
Source:
Biochemistry
Competition between Ski and CREB-binding protein for binding to Smad proteins in transforming growth factor-beta signaling
Wednesday, February 07, 2007
Author(s):
Weijun Chen,Suvana S Lam,Hema Srinath,Celia A Schiffer,William E Royer,Kai Lin
Source:
The Journal of biological chemistry
An optical signal correlated with the allosteric transition in Scapharca inaequivalvis HbI
Thursday, December 21, 2006
Author(s):
Jeffry C Nichols,William E Royer,Quentin H Gibson
Source:
Biochemistry
Low resolution crystal structure of Arenicola erythrocruorin: influence of coiled coils on the architecture of a megadalton respiratory protein
Tuesday, November 07, 2006
Author(s):
William E Royer,Michael N Omartian,James E Knapp
Source:
Journal of molecular biology
Lumbricus erythrocruorin at 3.5 A resolution: architecture of a megadalton respiratory complex
Tuesday, July 18, 2006
Author(s):
William E Royer,Hitesh Sharma,Kristen Strand,James E Knapp,Balaji Bhyravbhatla
Source:
Structure (London, England : 1993)
Allosteric action in real time: time-resolved crystallographic studies of a cooperative dimeric hemoglobin
Thursday, May 11, 2006
Author(s):
James E Knapp,Reinhard Pahl,Vukica Srajer,William E Royer
Source:
Proceedings of the National Academy of Sciences of the United States of America
Residue F4 plays a key role in modulating oxygen affinity and cooperativity in Scapharca dimeric hemoglobin
Thursday, November 03, 2005
Author(s):
James E Knapp,Michele A Bonham,Quentin H Gibson,Jeffry C Nichols,William E Royer
Source:
Biochemistry
Allosteric hemoglobin assembly: diversity and similarity
Saturday, June 04, 2005
Author(s):
William E Royer,Hao Zhu,Thomas A Gorr,Jason F Flores,James E Knapp
Source:
The Journal of biological chemistry
Sulfide binding is mediated by zinc ions discovered in the crystal structure of a hydrothermal vent tubeworm hemoglobin
Wednesday, February 16, 2005
Author(s):
Jason F Flores,Charles R Fisher,Susan L Carney,Brian N Green,John K Freytag,Stephen W Schaeffer,William E Royer
Source:
Proceedings of the National Academy of Sciences of the United States of America
Crystal structure of the hemoglobin dodecamer from Lumbricus erythrocruorin: allosteric core of giant annelid respiratory complexes
Wednesday, October 27, 2004
Author(s):
Kristen Strand,James E Knapp,Balaji Bhyravbhatla,William E Royer
Source:
Journal of molecular biology
Immobilization of Scapharca HbI crystals improves data quality in time-resolved crystallographic experiments
Wednesday, March 24, 2004
Author(s):
James E Knapp,Vukica Srajer,Reinhard Pahl,William E Royer
Source:
Micron (Oxford, England : 1993)
Catalytic implications from the Drosophila protein L-isoaspartyl methyltransferase structure and site-directed mutagenesis
Wednesday, November 05, 2003
Author(s):
Eric J Bennett,Jens Bjerregaard,James E Knapp,David A Chavous,Alan M Friedman,William E Royer,Clare M O'Connor
Source:
Biochemistry
Ligand-linked structural transitions in crystals of a cooperative dimeric hemoglobin
Wednesday, April 23, 2003
Author(s):
James E Knapp,William E Royer
Source:
Biochemistry
Back To Top ▲
