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About

Located in Worcester, Massachusetts, the UMass Cancer Center is committed to providing exceptional patient care, conducting cutting-edge research at the highest level, offering excellence in education and training, and serving as an educational resource and advocate for the Central Massachusetts community.
Patients
Patients

Expert Cancer Care in Central Massachusetts

We offer comprehensive cancer care for all childhood and adult cancers, combining state-of-the-art treatments with compassionate support for patients and their families.
Clinicians
Research
Research

Cutting-Edge Cancer Research

We carry out front-line research in basic, translational, clinical and population-based discovery to find newer, better methods for the prevention, detection, diagnosis, and treatment of cancer.
Education
Education

World Class Medical and Scientific Education

The UMass Cancer Center is dedicated to training the next generation of cancer researchers, clinicians and physician-scientists.
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Additional Resources

Fiachra Humphries, PhD

Assistant Professor, Department of Medicine/Division of Innate Immunity

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Fiachra Humphries, PhD

Research Focus - Defining How Innate Immune Shapes the Tumor Microenvironment

The role of type I IFN in the tumor microenvironment
Regulation of tumor associated macrophages
Regulation of tumor cell pyroptosis
Regulation of tumor cell ferroptosis
Plasma membrane rupture in tumor cells

Representative Publication

Jiang Y, Yang Y, Hu Y, et al. Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade. Cell Rep. 2022;41(4):111553.

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More Publications

In the News

Getting Results…

UMass Chan faculty present translational research at BRIDGE Fund Innovation Showcase

UMass Chan supports translational research from faculty with internal funding mechanism.

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UMass Chan BRIDGE Fund invests nearly $2M in 13 faculty projects

The BRIDGE Fund supports critical research milestones for inventions and discoveries that have high potential to change the course of disease and continues to grow, increasing from approximately $1 million per year in 2019 to $3 million in 2024.

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